Journal: Glia
Article Title: Astroglial endfeet exhibit distinct Ca 2+ signals during hypoosmotic conditions.
doi: 10.1002/glia.23692
Figure Lengend Snippet: FIGURE 3 Impact of dystrophin deficiency and TRPV4 blockage on endfoot Ca2+ responses to hypoosmotic stress. (a) As in Figure 1c, but traces are from endfeet of mice lacking dystrophin (mdx3Cv mice). (b) As in Figure 2b, but values are from mdx3Cv (gray bars) and wildtype (white bars) mice. (c) As in Figure 2c, but values are from mdx3Cv (gray) and wildtype (white) mice. (d) As in Figure 2d, but values are from mdx3Cv
Article Snippet: In some experiments, 1 μM of the TRPV4 channel antagonist HC067047 (2-methyl-1-[3-(4-morpholinyl) propyl]-5-phenyl-N-[3-(trifluoromethyl)phenyl]-1H-pyrrole-3-carbox- amide; Tocris Bioscience, stock solution 10 mM in DMSO), was added to both the normosmotic and the −20% hypo- osmotic aCSF.
Techniques: